I hope everyone is having a good week.

The Alzheimer’s Association International Conference is underway in London. Yesterday, Eisai and Biogen issued a joint statement with results of the real-world Lecanemab in Early Alzheimer's Disease (LEADER) Study. I have been anxiously waiting for these results. Especially, this statement:

“Nearly 83% of early Alzheimer's disease (AD) patients enrolled in the study remained stable (75.9%) or improved (6.6%) while receiving LEQEMBI^® therapy over an average of 17 months.”

Is the inconvenience of the bi-weekly infusions, the injection side effects, the ARIA risk, and the high cost of Lecanemab worth having your Alzheimer’s remain stable?

Certainly, remaining stable is much better than progressing. Are there options with better results?

The results of the Phase II-III trials of the Cuban developed drug, NeuroEPO (NeuralCIM) were positive:

• More than 80% of the clinical trial participants showed their cognitive decline stopped.

• Cognition improved in 54% of the participants.

There are several challenges associated with NeuroEPO (NeuralCIM). The greatest concern is Trump deciding to invade Cuba.

Let’s discuss the Lecanemab LEADER Study. Please leave a comment with your thoughts.

I am doing about the same as I was a week ago. Late afternoons and nights are challenging in terms of my mood, anxiety, emotions, and depression.

Yesterday, I took a town bus to the grocery store and the bank. It was nice to get out for a few hours. The Chapel Hill bus service is fantastic - especially, since it is free. I suppose the bus service is a perk of living in a college town.

Thanks to those of you who made a donation since Monday. I greatly appreciate your support. I suggested a donation of $5 per day would adequately compensate me for my research and writing time, help Linda and I bridge our income gap, and hopefully, not be too painful for my subscribers. This morning, I quickly looked to see what $5 will buy in the United States. The short answer is - not much!

This is what I found:

• value-menu item like a McDouble or fries at McDonald’s

• medium drip coffee

• small fountain drink at a convenience store

• gallon of milk

• maybe a pound of apples or oranges

• bag of potato chips or cookies

If you have not donated, please consider clicking below and scheduling a monthly contribution.

$5 Donation

$10 Donation

Thank you!

There is poem called Small Kindness written by Danusha Laméris, that highlights how small gestures can make a huge difference. I think the poem also proves that we mostly just want to care for one another.

I’ve been thinking about the way, when you walk
down a crowded aisle, people pull in their legs
to let you by. Or how strangers still say “bless you”
when someone sneezes, a leftover
from the Bubonic plague. “Don’t die,” we are saying.
And sometimes, when you spill lemons
from your grocery bag, someone else will help you
pick them up. Mostly, we don’t want to harm each other.
We want to be handed our cup of coffee hot,
and to say thank you to the person handing it. To smile
at them and for them to smile back. For the waitress
to call us honey when she sets down the bowl of clam chowder,
and for the driver in the red pick-up truck to let us pass.
We have so little of each other, now. So far
from tribe and fire. Only these brief moments of exchange.
What if they are the true dwelling of the holy, these
fleeting temples we make together when we say, “Here,
have my seat,” “Go ahead—you first,” “I like your hat.”

Essentially, the poem suggests a fundamental human desire for kindness and mutual care in everyday interactions, from simple smiles to courteous gestures on the road.

Since my Alzheimer’s diagnosis last September, there have been numerous acts of kindness bestowed upon Linda and me. It doesn’t matter whether the act of kindness was large or small, it made a big difference for us. In early October, a close friend told me not to hesitate to ask for help. She said helping those in need is a core human value.

It is like I spilled my lemons, and I am asking people to help me pick them up. I still struggle with asking for help though. There is something in my DNA that makes reaching out with an open hand difficult - even painful.

The bottom line is that our Social Security and limited investments are not enough to cover our living expenses, rising medical costs, and eventual caregiver needs. We have a goal to bridge a $2,000 monthly income gap. I am still fully able to study, conduct research, speak, and write. I want to work for this income, and I want to invite you to help me do it. Let’s make lemonade together.

Here is how you can join our tribe and support us today:

• Subscribe to the Research Report: I summarize the most complex, technical, and scientific information on Alzheimer’s disease and emerging treatments into clear language. You can upgrade to a paid subscription for $10/month or a discounted annual rate of $100/year.

• Become a Founding Member of the Research Report: If you want to provide a deeper level of baseline stability for Linda and me, you can choose the $250/year Founding Member tier on Substack. Founding Members will join me monthly for a video conference to discuss emerging Alzheimer’s treatments in great detail.

• Support the blog, My Alzheimer’s Journey: There are nearly 500 free subscribers. If half of the subscribers donated $5 per month we would have gross donations of $1,250 each month.

• Direct Support: If you prefer a simple, one-time contribution rather than a recurring subscription, you can send a direct donation of any size.

• The Online Store: Our goal is not to grow the store into a juggernaut. Modest sales result in satisfactory profit. Sharing a link to the store with your friends and social networks will be extremely helpful.

• Paid Speaking Engagements: We believe I have a compelling story about navigating an Alzheimer’s diagnosis with dignity and resilience. Starting this week, we will begin reaching out to universities, medical advocacy groups, corporations, and civic organizations seeking speaking opportunities. You can help in a few ways:

  • developing a speakers package

  • representing me as an agent

  • recommending me to your employer or a civic organization you belong to

What are we doing to bridge the income gap?

• Since rent is our greatest expense, we are looking at several locations in North Carolina that offer more affordable housing. We are flexible to relocate since I am no longer required to be at Duke Health for infusions.

• We are reducing living expenses wherever possible. This is a challenge in the current inflationary economy.

• Several income producing opportunities have been suggested, and we are exploring those now. Among the opportunities are an e-book about my first year as an Alzheimer’s patient and converting many of the blog posts into YouTube videos.

Please join our tribe and help us on this difficult journey. You can contact me by email at greg@rowjeraholdings.com.

Thank you,

Greg & Linda

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As a South Carolina native and a political junkie, I have a deep understanding of Senator Graham’s legislative career. While Senator Graham and I rarely agreed on political matters, he was a good, kind, and decent human being. He was politically astute. He understood what the majority of South Carolinians wanted. From education to civil rights, Senator Graham worked hard in Washington to craft laws and guide them through the political process.

I find it fascinating that no matter how mad Senator Graham made the citizens of South Carolina, he always won reelection. I suppose that is indicative of his political prowess. Or, maybe his southern charm.

I recall four issues that resulted in significant backlash:

• Senator Graham angered conservative voters early in his Senate career by working with Democrats on comprehensive immigration reform, notably championing the DREAM Act.

• A fierce critic of Donald Trump in 2016, Senator Graham later became one of his staunchest allies. This dramatic shift alienated moderate Republicans and progressives who were frustrated by his loyalty to the former president.

• Senator Graham’s persistent advocacy for aggressive military intervention abroad - including continued support for conflicts in the Middle East and increased tensions with Iran - drew criticism from local voters and anti-war advocates who felt the policies were disconnected from South Carolina families

• Most recently, Senator Graham has been accused of prioritizing Washington D.C. politics and television appearances over local, constituent-focused work and town hall meetings.

As South Carolina’s political leanings are slowly changing, Senator Graham’s strict conservative beliefs are falling out of favor with many people. Due in large part to his absence in the state, Senator Graham faced strong opposition in this year’s election. Many people believe Democrat Dr. Annie Andrews has the best chance of taking over the Senate seat since Senator Graham won in 2002.

For now, the focus should be on honoring the man who gave so much to South Carolina.

Since my Alzheimer’s diagnosis, I often think about death. I study the end-of life process with the goal of preparing myself for the inevitable. In fact, I wrote a blog post November 7, 2025, about death.

Not everyone expects to die. Most people die from tragic accidents, violence, and sudden illness. Senator Graham did not expect to die last night. He was scheduled to appear on a television political program today. I suspect he had a busy week planned, and he was thinking about his schedule after returning from Ukraine. Suddenly, he had chest pains and efforts to revive him were unsuccessful.

With my curiosity about death, I researched how Senator Graham may have felt during his last hours and minutes. When experiencing chest pain, many people believe they are dying. This overwhelming fear is clinically known as a sense of impending doom. It is a recognized physiological and psychological warning sign often triggered by sudden changes in heart function or the nervous system during life-threatening medical events.1 The brain recognizes the danger and activates the primitive "fight-or-flight" response, which causes an intense surge of panic alongside physical symptoms - like, chest pains.

While science views death as the end of biological processes, many cultures and religions view it as a spiritual transition.

Not only does a person die, their hopes, dreams, plans, and careers cease to exist. Unless, someone picks up the torch and works to continue those dreams and plans. It would be a great honor for Senator Graham if the war in Ukraine can finally come to an end.

Most importantly, I hope Senator Graham died peacefully.

I will be walking around in a bright purple shirt next week. If you happen to see me, please don’t just stare at my back—feel free to whip out your phone and scan me.

I recently suggested to Greg that we should do something that raises awareness, raises a bit of money, and honestly, raises a smile. We can all use a smile!

The front explains exactly who the shirt is for. The back features a giant QR code and a reminder that... well, we forgot the rest of the message. If you want to see how the joke ends (and grab a shirt to help support Greg’s journey), click here and check it out.

Every shirt bought helps us back Greg up, raise his spirits, and show him that he is not alone on this journey. Let’s make some noise, wear some purple, and support my awesome husband.

Thanks!

Linda

A post on Reddit yesterday morning referred readers to a YouTube podcast about lifestyle changes that could reverse Alzheimer’s disease (AD). The video begins with Christine Carter saying, “Alzheimer’s can be reversed with lifestyle.” Of course, that is impossible.

The podcast is “Diacardia”, hosted by Dan Mulhern. Dan is an author and speaker. His expertise is leadership. He describes his podcast as:

Diacardia means "through the heart" or "between hearts." It's a podcast for two to listen and share. The heart is your core, the source of your power and your passion. It's also a precious place of vulnerability. It's wisely guarded. Diacardia is the practice of speaking from the heart and listening fully with the heart. When you do this practice, you grow, your partner grows, and your relationship grows.

Christine Carter has a PhD in sociology. Her website offers this brief bio:

Christine Carter, Ph.D. is one of the most credible voices in the science of human flourishing. A Harvard Medical School-trained Wellness and Lifestyle Coach, Senior Fellow at UC Berkeley’s Greater Good Science Center, and member of the American College of Lifestyle Medicine, Dr. Carter has spent over two decades translating research into practical tools that actually change lives. Her work has been featured everywhere from The New York Times and the Washington Post to Oprah, The Today Show, and The Daily Show with Jon Stewart.

Alzheimer’s disease can’t be reversed. Alzheimer's pathology is driven by the accumulation of two proteins in the brain: amyloid beta plaques and tau neurofibrillary tangles. These proteins eventually lead to irreversible cell death and brain atrophy.

I am writing an article on cognitive decline for Greg’s Alzheimer’s Research Report. As part of my research, I reviewed work conducted at the Netherlands Institute for Neuroscience. The lead scientist, Evgenia Salta, has this quote as part of her bio:

“If a computer crashes, you can press control-alt-delete to restart the whole thing. But if your brain crashes, like Alzheimer’s and other neurodegenerative diseases, you can’t. In neurodegenerative diseases, nerve cells become damaged and die, causing the brain to increasingly falter. Well-known examples are Alzheimer's, Parkinson's and huntington. Often, medications can alleviate the symptoms associated with these conditions, and sometimes they can slow the course. But healing is still not possible.

“Healing is not possible.”

As someone suffering from Alzheimer’s, and as an Alzheimer’s advocate, the podcast concerns me because false claims give people false hope. I agree that a healthy lifestyle can help manage Alzheimer’s symptoms and possibly slow the disease progression. Reversing Alzheimer’s is not possible with a healthy lifestyle.

There are many false hopes for Alzheimer’s patients and their families offered by dozens of “snake oil salesman”. Their fraudulent remedies, cures, and solutions are valueless. Let’s look a few of these questionable solutions:

• Robert W. B. Love operates a Florida clinic that sells a wide variety of supplements. On his Instagram videos, he says he is a neuroscientist and that he has a “medical clinic in Florida helping people prevent Alzheimer’s”. A recent video has Dr. Josh Helman as a guest, and he states that to prevent AD you need to avoid eating fried foods. One of the reasons he states is that fried foods contain acrylamide - a proven neurotoxin. It is believed that acrylamide plays a role in cognitive decline; however, there have been no studies proving acrylamide is a direct cause of AD. For a variety of health reasons, we should limit our consumption of fried foods.

• In another Instagram posted by Robert Love, he states there are three supplements that “prevent and reverse” AD. I agree the supplements he recommends may be helpful in managing AD symptoms. My concern is the video presentation and his choice of words.

• There is woman who produces and posts video on Instagram and TikTok. Her screen name is jaemamajams. I do not know anything about her credentials. In a December 31, 2025 Instagram video she states, “a new study shows that Alzheimer’s disease can be reversed to achieve full neurological recovery.” The study she references was testing the effects of NAD+ on mice. The results are promising; however, there have been no trials on humans.

• Dr. Kevin Reese is the creator of Head-To-Toe Healing. He has an Instagram video where he states he has seen people “correct AD” and have “better cognitive function than before they had AD”. He also says, “the medical monopoly doesn’t know how to correct any brain condition.”

In addition to the videos posted on social media, there are hundreds of advertisements for a range of supplements, food products, and devices. I saw an advertisement on Instagram this morning for a “hand steadiness device” that reduces hand tremors. The price is $337.55 (reduced to $270.04). It doesn’t seem to have a $270 value.

These products, supplements, books, etc. generally target people who are desperate for a cure or a magic anything to reduce their pain. Not all, but many, of the products make false or exaggerated claims. Ultimately, people get false hope, and they purchase products that may have zero real benefit.

The only solution is for the consumer to be aware and cautious. The sellers of these products rarely break any laws. Telling a lie is only a legal problem if the lie causes harm.

In my mind, many of these advertisements and videos cross my ethical line. I know that as cultures evolve, new technologies emerge, and our collective understanding of human rights deepens, society re-evaluates what is considered right and wrong. I suppose, I should get with the times and adjust my ethical line. Nay, I like my ethical boundary right where it is.

How Am I Doing?

I have not noticed much change in my cognitive function in the past week. My hand trembles are more frequent. I often get cold flashes. Depression and sadness are constant companions.

My studying and writing keep my mind active. Writing this blog and the research report give me a purpose in life. Linda and I work together on our online stores. It is very difficult to start a successful online store. The competition is great and the search engine algorithms are challenging. This is why I ask you to spread the word among your social network and friends.

I take life one day at a time.

Thank you for your continued support.

My Alzheimer’s Journey is made possible by reader and subscriber donations. If you’re able to, please consider contributing so I can continue to share insight with you and the many caregivers and families who are following My Alzheimer’s Journey.

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Are you interested in learning about Alzheimer’s emerging treatments and related developments? Visit my research report.

America will be 250 years old tomorrow.

I remember the bicentennial very well. I was a high school student in a somewhat small town in South Carolina. There were parades with marching bands and fire trucks. People decorated their homes with red, white, and blue ribbons, wreathes, and flags. Friends, neighbors, and families expressed feelings of patriotism and nostalgia. The Civil Rights Movement, the Vietnam War, and the Watergate crisis were in our rearview mirror. It was a fun celebration.

Everything feels different fifty years later.

I find it difficult to celebrate the 250th anniversary of a democracy that is becoming less democratic right before our eyes. America’s democracy is built on a foundation of constitutional freedoms. Many of our freedoms are being compromised, altered, or shattered. The greatest freedoms that I feel have been damaged are freedom of the press and freedom of speech. Both are being restricted and muffled.

I can’t even imagine what America will be in fifty years.

In addition to wishing the country returns to a true sense of patriotism - respect for the constitution, and an understanding that all Americans matter - regardless of sexual orientation, religious beliefs (or none), color of skin, and political tenants, I hope there is a cure for Alzheimer’s.

I believe a cure will be discovered in the next twenty years. It seems like the cure for Alzheimer’s is a giant puzzle with dozens of missing pieces. Slowly, the missing pieces are discovered. As a first step, researchers are moving closer to understanding the cause of this horrible disease. I think there will be strong preventive measures available long before a cure is discovered. Let’s hope so.

It will require a lot of money and strong international teamwork to complete the Alzheimer’s cure puzzle. Sadly, just as our democracy is at risk of failing, so is the desire for both government and private organizations to make the needed sacrifices to fund Alzheimer’s research. The resources are readily available to discover the cause of Alzheimer’s and ultimately, develop the cure. In my opinion, the priorities of the people and organizations that control the needed resources are fucked up misguided, selfish, and narcissistic.

Seven million Americans are dying from Alzheimer’s as the country celebrates its semiquincentennial (250th anniversary) this weekend. By 2050, that number will likely double.

Please explain to me how finding a cure for Alzheimer’s is not an urgent priority.

I hope everyone has a safe and fun celebration of the 250th anniversary of America. Linda and I will have a quiet weekend at home. We are so grateful for the many people who support us in their thoughts, prayers, and gifts.

My Alzheimer’s Journey is made possible by reader and subscriber donations. If you’re able to, please consider contributing so I can continue to share insight with you and the many caregivers and families who are following My Alzheimer’s Journey.

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Are you interested in learning about Alzheimer’s emerging treatments and related developments? Visit my research report.

Alzheimer's is a highly individualized disease.

My journey is proof that there are no certainties with Alzheimer’s. Short-term memory loss is the only Alzheimer’s symptom that is common among most patients. I am learning that there is no set sequence or intensity of the progression of Alzheimer’s.

Based on my research, there are five primary types of symptoms:

• Cognitive Decline

• Language and Communication

• Spatial & Visual Issues

• Mood & Personality

• Motor Skills

How an Alzheimer’s patient moves through those symptoms - or even which symptoms they experience - seems to be a crap shoot. This is because the brain is impacted differently in each individual, the early and progressive signs often depend on where the disease originates in the brain.

I only slept a few hours last night. A few cat naps today helped me rest and recharge my batteries. Hopefully, I will sleep better tonight.

My sun downing is getting worse. For seemingly no reason, I become very emotional in the evenings. Actually, there is a reason - Alzheimer’s!

The chills continue on a frequent basis. My hands tremble to the extent that putting toothpaste on my toothbrush is a challenge. There is also a nagging issue with my voice changing.

Not to be all sad and only have bad news, today was actually a good day.

Linda’s Home Care Physical Therapist visited today. Linda is doing better and using a walker more frequently than the wheelchair. We walked to the community gym and Linda used a few machines as part of her rehabilitation routine.

I need to start visiting the gym, In recent months, I have added a few pounds and my body is expanding. The drugs I take must be the cause of my weight gain. It certainly can’t be my fondness for all things sweet.

This afternoon, the cats had a visit from the groomers who trimmed their nails. Big Bit and Bella have zero issues getting their nails trimmed. Lola hates the procedure. She even growled at the woman holding her.

I look forward to Big Bit not scratching my face tonight.

My Alzheimer’s Journey is made possible by reader and subscriber donations. If you’re able to, please consider contributing so I can continue to share insight with you and the many caregivers and families who are following My Alzheimer’s Journey.

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Are you interested in learning about Alzheimer’s emerging treatments and related developments? Visit my research report.

When I wake up in the mornings, I am often confused and uncertain where I am. Lately, the confusion of my location is combined with thoughts of my deceased parents. In my thoughts, I will plan going to visit mother and dad. As unpredictable as those thoughts appear, they vanish.

For the first time, I experienced location confusion in the afternoon Wednesday. I was laying in the bed reading and suddenly, I felt lost. I had no idea where I was. This lasted a few minutes.

This confusion is a small portion of my typical day. I hope it stays that way for a long time.

I am able to read, study, and research very complex scientific topics. My writing skill hasn’t changed except for leaving words out as I type. I must work in a quiet environment, or I become distracted and anxious. Linda would probably say I get annoyed and agitated by distractions - especially, noise.

A few days ago, I remained confused, sad, and depressed the entire day. After Linda and I ate dinner, I became dizzy and I had trouble walking. My blood pressure was well below my normal range. Both of us were a tad concerned. The next morning I felt much better and my blood pressure was in my normal range.

Due to the extreme heat, I have not been walking very much. When I do walk, I quickly get winded and tired. Of course, I drink a lot of water to stay hydrated.

Overall, I am doing well. I see glimpses of the future though. I don’t like what I see.

My life is so different from a year ago. Going from working at least ten hours each day, to having no set schedule has been difficult. If there were a workaholic gene, I would have it. Not just me, my brother and sister would also have it. My dad worked very hard most of his life and he instilled that strong work ethic on all of us. Or, maybe it is a special gene we have.

I am learning to enjoy not having a set schedule. My Alzheimer’s disease has zapped my energy, so I nap often. I call them cat naps. There is always at least one cat beside me when I nap.

Linda and I definitely feel a burden has been lifted since our house sold. We have no financial or legal ties to Spartanburg now. We continue to struggle to make ends meet. Our greatest challenge is the cost of housing. Our two bedroom, two-bathroom apartment rent is about $2100. That is crazy. We have begun looking for less expensive housing. We are finding that our current rent is at the lower end of the average range in the area. The search continues.

If we can’t reduce our rent cost, we must increase our income. I believe we have a solid plan to earn a modest income from a few different ventures. It takes time to develop those ventures though. Below is an update on our online store. This is a plan that came about after a lot of analysis, consulting with ecommerce experts, and soul-searching to determine how much work Linda and I can handle. I apologize for the length of the plan.

Carrying the Message: Why We Remodeled Greg’s AZ Store (And How You Can Help Us Outsmart the Algorithms)

Every day, I dedicate myself to raising awareness for Alzheimer’s disease and honoring the incredible caregivers who stand by their loved ones. Through this blog and my recently launched research reports publication, I share vital information to Alzheimer’s patients, caregiver’s, medical professionals, and others who are interested in learning about Alzheimer’s. But words on a screen can only go so far. To truly weave this cause into the fabric of everyday life, I need something visual, conversational, and close to the heart.

That is partly why I created Greg’s AZ Store. The other reason (very important reason) is to have a source of income.

Linda and I recently completed a total remodel of the store and completely updated our merchandise with a beautiful new philosophy: subtle, low-key advocacy.

Subtle Style, Big Conversations

Based on feedback from customers and friends, the new apparel features quiet, subtle graphic messages. We intentionally designed these pieces to appeal to everyone - even those with no direct connection to Alzheimer’s. I clearly understand that not everyone wants to wear a tee-shirt with a bold graphic message.

My goal is simple. I want people to look at your awareness apparel and ask, “What does that design mean?”

Every time they do, it opens a door. It gives you a gentle, natural opportunity to talk about the importance of treatment research, the desperate need for a cure, and the power of disease acceptance.

I have also doubled down on quality and sustainability. We are now using top-tier, eco-friendly brands, including Bella + Canvas, Comfort Colors, Stanley/Stella, and Rabbit Skins for kids.

One of my absolute personal favorites? Our new brain athletic shorts and joggers. They are completely unique, incredibly comfortable, and guaranteed to catch people’s eyes at the gym or on a run.

The “Cat Man” Challenge: Let’s Go Global

To get this message moving, I want to steal a brilliant idea from a quirky grocery chain called Stew Leonard’s. Decades ago, a shopper took a photo with one of their grocery bags in front of Moscow’s St. Basil’s Cathedral.

The owners loved it and encouraged others to do the same. Today, thousands of photos of their mascot, Clover the Cow, have been sent in from all over the world, creating a massive, joyful community movement. The photos are posted in their stores and on Instagram.

We have our own incredible icon: the Cat Man logo.

Let’s start our own movement. Pack your Cat Man apparel when you travel. Wear it to local landmarks, your favorite hiking spots, or everyday neighborhood hangouts. Snap a photo and email it to me at greg@rowjeraholdings.com. Let’s see how far across the globe we can carry the message of Alzheimer’s awareness together!

Why We Need You (Outsmarting the Algorithm)

Finally, I need to share a challenge we are facing, and transparency is important to me.

Because the store promotes that the profit supports my medical, living, and eventual caregiving expenses, Google’s policies categorize our store as an unapproved fundraising entity. Google prohibits the use of its shopping network to raise money for health-related causes.

As a result, Google will not allow us to advertise, and we will not appear if someone searches for “Alzheimer’s Awareness apparel.”

I cannot rely on big tech algorithms to spread this message. I can only rely on you. The only way people find our store is if they type the address directly or click a link from another website, blog, etc.

How You Can Help Right Now

Linda and I cannot do this alone, but together with you, we can be an unstoppable force. Here is how you can help us make a difference today:

1. Share the Link: Copy GregsAZstore.com and share it across your Facebook, X, Instagram, or LinkedIn accounts. Tell your friends why this cause matters to you. To make it easy to tell the story, you may want to share the link to my personal website: gregoryrowland.com

2. Start a Conversation: Buy a pair of the new brain joggers, brain shorts, or a subtle polo shirt, wear it out, and watch the seeds of awareness grow.

3. Join the Photo Movement: Snap a picture rocking your Cat Man gear and send it to greg@rowjeraholdings.com.

Your support means the world to me, to caregivers, and to everyone fighting this disease. Let’s bypass the search engines and build my brand awareness the old fashion way.

With deep gratitude,

Greg

Welcome to the new subscribers. You are now a member of My Alzheimer’s Journey family.

When I moved the research articles to a separate publication, I stated that the primary reason was to give clarity to each publication. There is a significant difference between the two publications. In addition to the obvious difference in topics, the writing styles and voices are distinct.

Starting today, My Alzheimer’s Journey will be even more personal, casual, and raw; than it has been in recent months. In a sense, I am taking the blog back to its roots. I believe most of you are interested in learning about my personal experience living with Alzheimer’s. My goal has always been to openly share my life as someone living with Alzheimer’s. The objective is for everyone reading this blog to learn from my experience.

Even if you are not directly impacted by Alzheimer’s, I believe my experience provides valuable insight into how to manage the challenges all of us face as we wander through life. Additionally, I want to learn from you. Let’s make the blog a conversation.

Today’s subject, ‘Alzheimer’s Really Does Suck’ is exactly how I felt the past couple of weeks. Between, chills, frequent memory failures, increasing confusion, trembling hands, and depression, Alzheimer’s did a number on me. This past weekend, I was alone with the cats since Linda went to visit family. That really sucked!

There is little doubt that my Alzheimer’s is advancing. It seems that the progression is centered on motor function and behavioral changes. I do not believe my cognitive abilities have decreased much in recent months. Regardless of how this awful disease progresses, the impact on quality of life is significant.

Last week, I had to sign closing documents for the house we sold in South Carolina. A notary and a witness came to our Chapel Hill apartment for the signing. My hands were trembling so much that I could barely sign the documents. This was embarrassing for me; although, Linda and the notary told me not to worry about it. I tried not to be concerned about my trembling - but, it bothered me.

I am becoming increasingly easily agitated. This seems to happen in the mornings and evenings. Yesterday, Linda’s flight arrived at the airport near our home about 3:30 in the afternoon. I had scheduled an Uber to pick her up. There were all sorts of challenges for Linda to get from the plane to baggage claim to the Uber. Her wheelchair complicated the journey. Something hiccuped with Uber (the driver was at the airport, but the ride request vanished from his system.) Bottom line, I was chatting with the Uber help desk, messaging the Uber driver, and texting Linda - all at the same time for an intense twenty minutes. I became agitated, confused, and overwhelmed.

A year or two ago, I could juggle multiple tasks, manage several projects simultaneously, and easily keep several lines of communication going at the same time. Not only could I do those things, I remained relatively calm. Not today.

There are many triggers for my agitation. I believe the list of triggers is increasing. Linda and I know the triggers, and we do our best to avoid them. The most common agitation triggers are loud noises, chaotic activity, and frequent interruptions of my activities.

The best remedy when I get agitated is to spend time with Big Bit, my emotional support cat. She is the best at calming me down.

Staying busy is also important for my mood. I am not very good at watching movies or television for long periods of time. I like to be productive. Therefore, I spend hours every day researching and writing. Working on our online store also keeps me busy.

Speaking of the store, I did a major remodel and reorganization while Linda was away. We decided to remove all products not related to Alzheimer’s and caregiving. Greg’s AZ Store is now living up to its name. Take a look, and please don’t be bashful to shop a bit. Suggestions for store improvements and products are always welcome.

I will focus on the research publication the rest of this week. You can expect another blog post Saturday.

I am deeply appreciative of your support and dedication to following my Alzheimer’s journey. It would be very lonely without you walking beside me.

Greg’s Alzheimer’s Research Report

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Happy Juneteenth to those of you in the United States.

I had a really great experience yesterday. An experience that made me realize that there are a lot of good people in this crazy and divided world.

Linda and I rented a car yesterday so we could take care of several errands and appointments. Our last stop of the day was haircuts. After my haircut was finished, Linda dropped me off at a neighborhood pub, and she went to her salon.

West 94th Street Pub holds a lot of memories for me. Many years ago, I lived close to the bar and I became a regular patron. This place is very much like Cheers. Small, friendly, and welcoming to all who walk through the door.

The bartender and I were chatting about all sorts of things. Then a couple sitting around the corner of the bar from me joined the conversation when they overheard me mention the name of my hometown. The couple previously lived in Spartanburg. Soon, a gentleman sat down beside. All the while we are enjoying getting to know a bit about each other. As you may expect, my Alzheimer’s journey was part of the conversation.

The gentleman beside me told the bartender (Jason) that he was moving to a high top table because his daughter was going to join him.

Maybe thirty minutes later, Linda sent me a text stating she was leaving the salon to pick me up. As I was preparing to leave, Jason handed me a small piece of paper. He said it had been left on the table where the man and his daughter had eaten. The paper contained a sketch of me at the bar.

No note, no signature, just a really awesome sketch.

I absolutely love the sketch. More importantly, is the kind gesture that the sketch represents.

I posted this story on Reddit last night hoping the man or his daughter would see it. I want to personally thank the extremely talented artist.

My story doesn’t end just yet.

The outpouring of love, support, and kindness from Redditors has moved me beyond words. There have been 19,000 views and over 250 likes of my post. Durham and Chapel Hill are amazing cities. Both are college towns where people are open-minded, friendly, and supportive of strangers.

As someone struggling with Alzheimer’s, moments of joy can be infrequent and fleeting. Especially, this week. I have not felt the best all week.

To the still unknown artist and my fellow Redditors, thank you for lifting my spirits and giving me a bit of hope that there are good people full of love surrounding me.

Linda and I also went to the UNC Sports Medicine Clinic yesterday for a checkup on her leg injury. The fracture is healing slowly. The full leg brace has been replaced with a shorter and less bulky version. Linda is super happy about the brace change.

We planned to drive to Maryland today to celebrate Linda’s mother’s 93rd birthday. At the last minute, we decided I wasn’t feeling well enough to make the trip. Linda flew to Washington today, and she will return home Monday. She has arrived safely. Apparently, flying with your own wheelchair is a big hassle.

Please forgive any mistakes in this blog post. Linda is not available to proofread my writing. I did read the post to the three cats, and they indicated by meowing that everything is good.

Have a great weekend, and thank you for your continued support. It means the world to me.

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Hello, Friends.

Before I give you an update on my Alzheimer’s Journey, I have to express Linda’s and my excitement that the Carolina Hurricanes won the Stanley Cup.

As I expressed previously, I have never been a fan of organized sports. I simply focused on other interests and pursuits. Now, that AD has changed so many aspects of my life, I have time available to watch a few games.

I have become a big fan of the Carolina Hurricanes. It is rather difficult not to be a supporter of this awesome hometown hockey team. Last night, the Hurricanes won the Stanley Cup by beating the Las Vegas Golden Knights 3 to 0.

The excitement of the team, the Hurricanes organization, and the community is almost indescribable. Last night’s game was held in Las Vegas. There were numerous watch parties held in Chapel Hill, Durham, and Raleigh. The celebrations after the game were joyous, happy, and prideful.

The excitement is contagious. The Hurricane’s win actually made me happy.

I will write an article later today about the mental health benefits of being a sports fan. The article will be published in Greg’s Alzheimer’s Research Report.

Over the weekend, I toke a corticosteroid Friday, Saturday, and Sunday, It reduced the frequency of my chills substantially. I had a severe chill early this morning. I assume the chills will continue to taper off as my immune system returns to normal.

Thanks to everyone who sent me notes. Your encouraging words are appreciated.

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As I explained a few days ago, I am struggling with frequent chills accompanied by clammy skin. The persistence and severity of the chills are negatively impacting my sleep and my overall mental health. Stress and poor sleep accelerate cognitive decline and worsen brain health.

After a thorough medical exam, my awesome team at Duke Neurology determined the most likely cause of my chills is a reaction to Lecanemab. It was decided yesterday that I should stop the Lecanemab infusions. Additionally, I will take medication starting today to manage and hopefully eliminate the chills.

It will take about two months for Lecanemab to leave my body. In a few weeks, the results of the Syn-One test will be available. With a clean immune system and the knowledge provided by the Syn-One test, Duke Neurology will determine the best treatment path going forward.

To understand why I am reacting to Lecanemab with chills, we have to review Alzheimer’s characteristics, and how Lecanemab works.

Alzheimer’s is either caused by the onset of amyloid plaques in the brain or amyloid plaques are the result of Alzheimer’s. Regardless, toxic protein particles—known as oligomers—are the building blocks of amyloid plaques. The toxic protein particles ultimately cause neuronal death and eventually Alzheimer’s. In a healthy brain, microglia, the brain's immune cells, actively clear and destroy the toxic proteins.

Microglia can become overwhelmed, sluggish, or chronically inflamed. Eventually, their clearing capacity drops below the rate of protein production. The toxic particles begin to escape destruction, pile up, and eventually form the neurodegenerative plaques and tangles that drive diseases like Alzheimer’s.

Lecanemab is a monoclonal antibody (a protein that helps your immune system target specific proteins for removal), and it is designed to remove amyloid beta from the brain. However, “associated side effects have compromised its efficacy, and little is known about how this antibody is able to clear the toxic aggregates.”1

Chills are triggered by the immune system to artificially raise the body's temperature and fight off infections. White blood cells release chemical signals that "trick" the brain's thermostat into demanding a higher temperature. Because the body's actual temperature is lower than this new target, it initiates involuntary muscle contractions - shivering - to generate heat.

Another factor is that the brain damage associated with Alzheimer’s impairs the hypothalamus, the body’s internal thermostat. This disruption compromises the autoregulation system, preventing the brain from properly sensing temperature changes, communicating discomfort, or regulating blood flow to the hands and feet to maintain core body heat.

As I understand, there are two possible causes of my chills:

• something about Lecanemab altering my immune system

• Alzheimer’s has damaged my body’s thermostat (this is unlikely since my Alzheimer’s is in early stages)

Frankly, I find my situation an important part of the mystery of Alzheimer’s disease. Thousands of brilliant researchers are working around the globe to learn the cause of AD, how to best slow the progression of AD, and eventually prevent and/or cure AD. Maybe my chills will play a tiny part in improving future drug development.

Have a great weekend everyone. Thank you for your continued support.

Yesterday, Duke Neurology decided that I should skip my scheduled infusion today and instead go to a Duke Urgent Care Clinic for a checkup.

Linda and I went early this morning. Over the span of maybe two hours, I was poked, prodded, X-rayed, EKG’d, and drained of a fair amount of blood. The results were good. No problems below my brain.

The issue is that my immune system doesn’t like Lecanemab. Thank goodness for my heated Linus blanket and Big Bit. They keep me warm when the chills roll in.

The brilliant medical team at Duke are discussing the best path forward.

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On this day in 1882, the electric iron was patented by New York inventor Henry W. Seely. It weighed almost 15 pounds and was very slow to heat up. The iron is headed down the road to obsoletion - at least in most modern households. I suspect there are many young adults that have never used an iron. Out of curiosity, I looked at Walmart.com to see what a 2026 iron cost. You can buy a fancy Rowenta Performance Steam Iron for $49.97. It weighs 3.85 pounds.

Continuing to feed my curiosity, I searched for the latest household gadget in 2026. The winner is the Roborock Saros Z70 robotic vacuum. This is an amazing gadget. You can even have a conversation with it. Me: “yo, you missed some cat hair over there.” Saros: “you don’t pay me enough to be perfect.” Me: “excuse me, your list price is $2,599.”

Speaking of not being paid enough.

While awake at three o’clock this morning, I read on Reddit about several part-time jobs available in the Charlotte North Carolina area. The job seemed fairly easy. Your responsibility included restocking publications in grocery stores. The free crap at the front of the store. Someone asked how much the job paid. The answer was $16 per hour plus mileage. The person that asked went berserk. He thought the job should pay at least $20 per hour. It is a freaking part-time job. Very few brain cells are required. Can you lift ten pounds? Do you have a clean driving record? Great - start tomorrow.

Today is D-Day. Can you imagine what our lives would be like today if the sacrifices of World War II were not made 82 years ago? Could we spend $2,599 on a robotic vacuum? Maybe we would be smarter than to spend money to have a robot cleaning our floors.

You can’t think about D-Day without remembering the great leader, President Dwight Eisenhower. He was a true gentleman and statesman. One of my favorite Eisenhower quotes is, “I hate war as only a soldier who has lived it can, only as one who has seen its brutality, its stupidity." What do you think President Eisenhower would post on social media today?

Linda and I made plans to go to lunch a few days ago (a very rare event for us). We had to cancel our plans because I was not feeling well. I need to have my brain thermostat replaced. I get chills frequently. Apparently, my hypothalamus, which regulates body temperature is malfunctioning.

Today, we wanted to go to the local farmer’s market. We discovered that the town bus doesn’t pick up at the stop near our apartment on Saturday’s. We decided the correct bus stop was too far away with Linda in a wheelchair. Maybe next week, we can have an outing.

Those of you who know me well, know I am not much of a sports fan. Guess what? I am becoming a bit of a hockey fan. I lack proper knowledge of the rules of the game. At least I understand that the goal of the game is to slide the round puck into the netted tents. You have to get the puck past the big guy sitting in front the tent though. How am I doing?

Go Canes! It has been twenty years since the Carolina Hurricanes won the Stanley Cup. With me cheering for the Canes, surely, we will bring the cup back to Raleigh next week.

Speaking of next week. My mother would celebrate her 98th birthday on June 10. She died in 2012. I sure miss her. Also, our home in South Carolina should close next week. It is about damn time.

I guess that is enough random thoughts from my Alzheimer’s brain. It is time for my afternoon nap. I need to rest before the hockey game tonight. The one cool thing about Alzheimer’s is taking frequent naps.

Enjoy the rest of your weekend. Thank you for your continued support. It is great to have you beside me on my Alzheimer’s journey.

Hi Friends, Can you buy me a few cat treats?

Just click on the blue text. Thank you.

Big Bit

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Greg's Alzheimer's Research Report

I summarize the most complex, technical, and scientific information on Alzheimer's disease and new treatments, delivering it in clear, understandable language.

By Greg Rowland

Greg's Alzheimer's Research Report

Non-Drug Interventions For Alzheimer’s Disease

In recent years, there have been several new drugs introduced that either slow the progression of Alzheimer’s disease (AD) or treat specific symptoms. Scientists around the globe are researching and developing new therapies with the ultimate goal of curing AD. Often overlooked are the numerous non-drug interventions for AD…

Read more

a month ago · Greg Rowland

In recent years, there have been several new drugs introduced that either slow the progression of Alzheimer’s disease (AD) or treat specific symptoms. Scientists around the globe are researching and developing new therapies with the ultimate goal of curing AD. Often overlooked are the numerous non-drug interventions for AD.

Over the past few weeks, I studied non-drug strategies for managing AD symptoms, slowing cognitive decline, and improving the quality of life of an AD patient. Some of the suggestions I discovered were frankly a bit whacky. I ignored those recommendations and only considered evidence-based strategies.

Cognitive and Behavioral Therapies

• Cognitive Stimulation Therapy (CST): The goal of CST is to guide people with AD through a series of activities designed to promote continued learning so that they can stay mentally stimulated and socially engaged. Activities may include puzzles or games, playing instruments, or engaging in conversation with other group members and/or program facilitators. The social component of CST is extremely important; therefore, CST is most effective in group settings. Additional information: https://pmc.ncbi.nlm.nih.gov/articles/PMC12021387/

• Reminiscence Therapy: This therapy involves discussing past family and friend activities and events (vacations, grandchildren birthdays, weddings, etc) to stimulate memories. If possible, photos and videos, should be incorporated into the discussion. Reminiscence therapy works well in both group settings and one on one with a caregiver. There is evidence that reminiscence therapy is an effective technique for controlling aggressive behavior. Additional information: https://www.alz.org/help-support/caregiving/daily-care/reminiscence-and-reminiscence-therapy

• Reality Orientation: Generally structured as a group activity led by a trained caregiver or activity director, reality orientation helps to ground persons with AD with an understanding of time, place, and person. I often wake up confused about where I am and what day it is. I believe reality orientation may help me. Additional information: https://www.verywellhealth.com/treating-alzheimers-disease-with-reality-orientation-98682

• Cognitive Rehabilitation: Cognitive rehabilitation therapy has been defined by the American Congress of Rehabilitation Medicine as systematic and functionally oriented therapeutic cognitive activities directed to achieve functional changes by (1) reestablishing or strengthening previously learned patterns of behavior or (2) establishing new patterns of cognitive activity or compensatory mechanisms for impaired neurological systems. Additional information: https://www.healthline.com/health/mental-health/cognitive-rehabilitation#basics

Physical and Lifestyle Interventions

• Exercise: Ranging from a thirty-minute walk to strenuous aerobic routines, exercise has been proven to improve mental health, cognitive function, and manage depression. An added benefit of exercise is improving balance; therefore, reducing falls. Additional information:https://www.apa.org/monitor/2011/12/exercise

• Diet: Following brain-healthy eating patterns, such as the Mediterranean diet rich in vegetables, fruits, fatty fish, and healthy fats, helps manage vascular risk factors that contribute to cognitive decline. Additional information:

  https://my.clevelandclinic.org/health/articles/16037-mediterranean-diet

• Sleep and Stress Management: As I studied sleep and stress management, I realized this an area where I need help. The goal is to wake up and go to sleep at the exact same time daily to regulate your circadian rhythms. Other recommendations include: eliminating caffeine, and using soothing therapies like low-light environments, aromatherapy, and weighted blankets. I suggest feline therapy. It works wonders for me. Additional information:

  https://www.caregiveraction.org/alzheimers-and-sleep/

Music and Art Therapy

• Music Therapy: Research has shown that musical memories are often preserved from brain damage caused by AD. Patients who have lost the ability to speak can often hum, tap a beat, or sing lyrics to songs from their childhood. Music triggers memories, stimulates communication, reduces agitation, and builds confidence.

  Additional information: https://www.pacificneuroscienceinstitute.org/blog/brain-wellness-lifestyle/music-and-art-therapies-may-help-alzheimers-patients/

• Art Therapy: Without the need for prior skill, art therapy encourages non-verbal self-expression, reduces agitation, and improves communication. Drawing, painting, and sculpting give AD patients a way to creatively express emotions, feelings, and memories without relying on words. Additional information:

  https://arttherapy.org/what-is-art-therapy/

  I hope you find these non-drug therapies beneficial for yourself or your loved one.

As my Alzheimer’s disease (AD) seems to be progressing, so are my bouts of depression, or depressive episodes. In the past few weeks, I have often struggled to get out of bed and function normally.

October 13, 2025, I wrote an article titled, “The Link Between Depression and Alzheimer’s Disease.” Today, I want to dig a bit deeper so all of us are better equipped to handle our own depression, or a loved one’s depressive episodes.

While between 40% and 50% of AD patients have been diagnosed with depression, we must be cautious not to confuse cognitive impairment as depression - or vice versa. The following are behavioral symptoms of both depression and cognitive impairment:

• lowered self-esteem

• self-blame

• forgetfulness

• indecisiveness

Additional signs of depressions that are also signs of cognitive decline, include:

• hypomimia1

• apathy

• psychomotor slowness

• fatigue

• reluctance to communicate

Research studies have proven there is a relation between AD and depression. It is unknown (and often debated) whether depression is a preceding pathology and a risk factor for Alzheimer’s disease or it is a component of AD. Some studies indicate depression may act as both a risk factor and an early symptom of Alzheimer’s by contributing to brain changes such as elevated cortisol, inflammation, reduced nerve growth factors, and vascular damage, all of which accelerate cognitive decline.

I was diagnosed with Major Depressive Disorder (MDD) about eighteen years ago. I tend to believe that MDD was a risk factor and a symptom for my AD. My depression worsened significantly in early 2025 (about five months prior to my official AD diagnosis.) In fact, my primary care physician increased the dosage of my antidepressant medication in February 2025. I did not report my memory and cognitive decline until several months later. Looking back, that was dumbass decision I made.

Depression often occurs during the early and middle stages of AD. In my case, my depression seems to be worsening at the same time my AD symptoms appear to be progressing. It is certainly possible that I am slowing moving from early to middle stages of AD.

I must follow my own precautions though and not confuse depression as cognitive decline.

MDD is difficult to diagnose since there is not a definitive biomarker. In fact, MDD is considered a syndrome rather than a disease. Subjective questionnaires and behavior observation are generally used to diagnose MDD.

“Additionally, biological changes associated with Alzheimer’s, such as toxic plaque buildup in the brain, can predispose someone to depression. On the other hand, depression might trigger mechanisms that increase the risk of Alzheimer’s, making the relationship between the two conditions bidirectional and challenging to untangle.”2

I think the link between depression and AD should be a reminder that we need to take care of both our mental and cognitive health throughout life. Adopting these healthy habits can reduce the risks of both depression and AD:

• physical exercise

• balanced diet

• social engagement

• stress management

Most importantly, we should seek medical help at the first signs of depression or cognitive issues. Early diagnosis and effective treatment go hand in hand.

This is an informative video produced by the Integrative Memory Care Clinic at Emory University. I believe this video will help caregivers as they manage depression suffered by their loved ones.

I am going to go pet Big Bit, my emotional support cat. She seems to be a better treatment for my MDD than antidepressants.

I have always been a curious person. Tell me, show me, and let me learn the facts about everything I am involved in.

I woke up very early this morning with my curiosity in high gear. Why are my Lecanemab infusion side effects delayed a day or two after the infusion? With a cup of coffee in hand (thank you to the unknown person who sent the Cuisinart Grind & Brew Single-Serve Coffee Maker – I LOVE IT), I started digging deep into the internet.

The first thing I learned is that the 60-minute infusion only puts the Lecanemab into my bloodstream. None of the Lecanemab crosses the blood-brain barrier (BBB) during the actual infusion process. Crossing the BBB is a much slower, passive biological process that takes place over days and weeks after the infusion is complete. Based on several articles I read, this is a common misconception.

During the two weeks between infusions, about 0.1% of the Lecanemab in my blood crosses the BBB. This is inefficient! Researchers are working on new technologies to penetrate the BBB. Focused ultrasound seems promising.

While sipping coffee and petting Big Bit, I found an article that discussed the FDA’s Adverse Event Reporting System (FAERS). From that article, I jumped to the actual reporting system. For anyone who loves data, FAERS is your jam! This is a database that allows drilling down to the most detailed information you can imagine.

I went to Lecanemab and began digging. There are a lot of adverse events listed - even deaths. I think it is important to balance the adverse events with the benefits. I knew Lecanemab came with risks when I decided to take it. The adverse events are greater than I expected though.

My awesome primary infusion physician at Duke Neurology prescribes medications that successfully manage my adverse events. I am confident Duke takes every precaution possible to keep every patient taking Lecanemab as safe as possible.

Do all hospitals and infusion centers take those same precautions? I certainly hope so.

My only disappointment with Duke and Eisai Inc. (the lead company for Lecanemab’s development and the final decision maker) is the lack of full transparency during the treatment decision-making process. Linda and I met with several Duke Neurology staff, and they explained the two treatment options - Lecanemab and Donanemab. We were provided literature for both drugs. The risks were clearly explained. Yet, looking back, full transparency about adverse events was missing.

Let’s set the stage for that meeting. Linda and I were scared beyond words. We knew our world was being turned upside down due to my Alzheimer’s diagnosis. More importantly, we did not fully understand Alzheimer’s disease. We were unaware of current treatment research. At that moment at Duke, Lecanemab seemed to be my best treatment option.

After seventeen infusions, the scenario is much different than the day we agreed to take Lecanemab. I have become an amateur expert on Alzheimer’s disease, emerging treatments, research challenges, Lecanemab, and the horrible realities of the disease. I have experienced the adverse effects of Lecanemab - ranging from intense shaking during chills to painful body aches.

Today, I am an educated Alzheimer’s patient.

I would make the same decision today that we made at Duke in September 2025. I would choose Lecanemab as my best treatment option. My frustration is that more transparent information was not provided by both Duke and Eisai. Looking back, I believe enough information was provided about the risks of Lecanemab to meet regulatory and liability requirements, while positioning the drug as a great treatment for my Alzheimer’s.

As a life-long business owner, I understand the need to sell and keep revenue flowing. For pharmaceutical companies, revenue funds research. I also believe an educated consumer is a better long-term supporter of a product and manufacturer. In the case of Duke and Eisai, transparency about adverse effects would not have changed the decision I made. It would have made me prepared, set true expectations, and made me a happier patient.

In recent months, I have shared these thoughts with Eisai.

I believe a video with a patient talking about their Lecanemab experience is needed. Show the infusion process, explain the possible adverse events, suggest preparations for adverse events, show an MRI, and talk about the great potential benefits of Lecanemab. Create an informed patient, not a frightened one.

Time for more coffee. Have a great Sunday.

Greg

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This has been a busy and somewhat frustrating week for Linda and me.

Linda continues to have physical therapy in our apartment. It seems to be going according to plan. She is using a wheelchair less and a walker more.

My infusion went well Tuesday. I had no side effects Tuesday afternoon. About 1:00 am Wednesday, I became nauseated. About 5:00 am, I had severe pain (muscle aches) in my forearms. This pain continued throughout the day. I had to reschedule a doctor appointment.

I felt much better Thursday. Linda and I acted like cats all day. Long naps with breaks for a snack.

Early this morning, I woke with muscle aches in my right leg. I find it interesting that my Lecanemab infusion side effects are generally delayed several days after the infusion.

At 10:00 am today, I had a biopsy at Duke Neurology as the first step in the Syn-One Test. This is a comprehensive lab test that detects abnormal proteins in cutaneous nerves to diagnose neurodegenerative disorders. There are indications that I may have some form of Parkinsonism. The Syn-One test will provide the answers.

After the biopsy, I went upstairs in the neurology building to the home of the i-MIND Research Group. I am joining the i-MIND study as a participant. In simple terms, this study is trying to learn if retinal images can diagnose neurological diseases. I wrote about the i-MIND study in Greg’s Alzheimer’s Research Report yesterday.

To wrap up the week, we learned that the scheduled closing on our South Carolina home is delayed by a few days. Rather than June 2, the closing will probably be June 4. I am told the delay is a minor issue.

Subscribers to the blog continue to grow. Welcome to each and every new subscriber. Please leave a comment or ask a question. I want the blog to be a community where we share and learn together.

If you have not visited Greg’s AZ Store lately, there are many great summer shirts in stock. We have sizes and styles for all ages.

Have a wonderful weekend.

Greg

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